A lupus journal publishing basic, clinical, translational and epidemiological studies on all aspects of lupus and related diseases. An official journal of Lupus Foundation of America.

Lupus Science & Medicine® is a global, peer reviewed, open access online journal that provides a central point for publication of basic, clinical, translational, and epidemiological studies of all aspects of lupus and related diseases. An official journal of the Lupus Foundation of America (LFA), which is dedicated to advancing the science and medicine of lupus while offering support to ...

Lupus Science & Medicine® is a global, peer reviewed, open access online journal that provides a central point for publication of basic, clinical, translational, and epidemiological studies of all aspects of lupus and related diseases. The journal publishes research on lupus from fields including, but not limited to: rheumatology, dermatology, …

Lupus Science & Medicine® is a global, peer reviewed, open access, online journal that provides a central point for publication of basic, clinical, translational, and epidemiological studies of all aspects of lupus and related diseases. Research on lupus will be considered from fields including, but not limited to: rheumatology, dermatology, nephrology, immunology, pediatrics, cardiology ...

The paradigm of drug approval in SLE currently relies on successful large phase III randomised controlled trials and a set of primary, secondary and additional end points. Taken together, these outcomes offer a nuanced understanding of the efficacy and safety of the investigational agent. In this review, we thoroughly examine the main outcomes used in SLE trials and highlight unmet ...

2024年9月4日 · Bone involvement is a common cause of morbidity and disability in systemic lupus erythematosus (SLE). 1 This is both a consequence of the disease itself and treatments, including steroids.2 As survival has improved, this has also led to long-term conditions being more prevalent, including osteoporosis and the risk of fractures.Prevalence of osteoporosis is increased in SLE patients. In cohort ...

2024年9月4日 · The systemic lupus erythematosus Disease Activity Score (SLE-DAS) aims to provide a practical, accurate, and sensitive to change tool to measure the activity of SLE. 1 This new tool addresses the pitfalls of the previously available instruments. The SLE-DAS is useful in routine clinical practice to quantify global disease activity. It enables clinicians to accurately classify disease activity ...

2024年9月4日 · Immune dysregulation in systemic lupus erythematosus (SLE) results in the autoimmune manifestations of SLE, but also leads to an impaired immune response to pathogens and vulnerability to infections in SLE patients. These patients exhibit a complex immune dysfunction, characterized by both impaired cellular and humoral immunity alongside defects in innate immunity. This occurs even in the ...

Thanoua etΔal Lupus Science Medicine 216e365 doi11136lupus21365 1 Scoring systemic lupus erythematosus (SLE) disease activity with simple, rapid outcome measures Aikaterini Thanou , 1 Judith A James,1,2 Cristina Arriens , 1 Teresa Aberle,1 Eliza Chakravarty,1 Joseph Rawdon,1 Stavros Stavrakis,2 Joan T Merrill,1 Anca Askanase3 To cite: Thanou A, James JA, ...

AskanasefiAD, etfial Lupus Science Medicine 202411:e001124 doi:101136lupus-2023-001124 1 Disease- modifying therapies in systemic lupus erythematosus for extrarenal manifestations Anca D Askanase ,1 Richard A Furie,2 Maria Dall'Era,3 Andrew S Bomback,1 Andreas Schwarting,4,5 Ming-Hui Zhao,6 Ian N Bruce ,7 Munther Khamashta,8 Bernie Rubin,9 Angela Carroll,9 Mark Daniels,10 Roger Abramino Levy ,11