Nestin is an intermediate filament protein expressed in dividing cells during the early stages of development in the central nervous system, peripheral nervous system and in myogenic and other tissues. Upon differentiation, nestin becomes downregulated and is replaced by tissue-specific intermediate filament proteins.

巢蛋白（ Nestin ）是一种组成VI型中间纤维的蛋白质，最初作为一种神经上皮干细胞的标记蛋白得到发现 [5] ，其英语名称“Nestin”即为“neuroepithelial stem cell protein”（意为神经上皮干细胞蛋白）缩写 [6] 。

巢蛋白（Nestin）、SOX2、Notch1、HES1、HES3、E-钙粘素（E-cadherin）、闭合蛋白（occludin）。 放射状胶质细胞 波形蛋白（Vimentin）、巢蛋白（nestin）、PAX6、HES1、HES5、GFAP、GLAST、BLBP、TN-C、N-钙粘素（N-cadherin）、SOX2。

The neuroepithelial stem cell protein, or Nestin, is a cytoskeletal intermediate filament initially characterized in neural stem cells. However, current extensive evidence obtained in in vivo models and humans shows presence of Nestin+ cells with ...

Dec 25, 2024 · NES (Nestin) is a Protein Coding gene. Diseases associated with NES include Embryonal Carcinoma and Periventricular Leukomalacia. Among its related pathways are COPI-independent Golgi-to-ER retrograde traffic and Neural Stem Cells and Lineage-specific Markers.

Nestin is an intermediate filament first reported in neuroepithelial stem cells. Nestin expression could be found in a variety of tissues throughout all systems of the body, especially during tissue development and tissue regeneration processes. Aim of Review

Mar 14, 2018 · The neuroepithelial stem cell protein, or Nestin, is a cytoskeletal intermediate filament initially characterized in neural stem cells. However, current extensive evidence obtained in in vivo models and humans shows presence of Nestin+ cells with progenitor and/or regulatory functions in a number of additional tissues, remarkably bone marrow.

Jul 1, 2024 · In general, in nestin + stem cells and adult cells that re-express nestin after injury, nestin often directly affects cell biological behaviours such as proliferation, apoptosis and migration regulation in response to different tissue injuries.

巢蛋白（nestin）是神经干细胞，胰腺干细胞的标志分子，是中间纤维家族的成员，被列为第Ⅵ类中间纤维，其结构和分子量与其他的中间纤维成员有差异。

This review highlights the potential of nestin as a marker of multilineage stem/progenitor cells, and as a key factor in tissue development and tissue regeneration. The article discussed the current findings, limitations, and potential clinical implications or applications of nestin + cell …