Histiocytosis refers to many rare blood disorders where white blood cells called histiocytes build up in tissue. They cause inflammation and can lead to organ damage. Histiocytosis includes Langerhans cell histiocytosis, Erdheim-Chester disease and Rosai-Dorfman disease.

Histiocytosis is a generic name for a group of syndromes characterized by an abnormal increase in the number of certain immune cells called histiocytes. These include monocytes, macrophages, and dendritic cells.

In medicine, histiocytosis is an excessive number of histiocytes [1] (tissue macrophages), and the term is also often used to refer to a group of rare diseases which share this sign as a characteristic.

Histiocytosis is a general name for a group of disorders or "syndromes" that involve an abnormal increase in the number of specialized white blood cells that are called histiocytes. Recently, new knowledge about this family of diseases has led experts to develop a new classification.

Histiocytosis (HIS-tee-oh-sy-TOH-sis) is a family of rare diseases that affect only a few hundred people each year in the United States. A type of white blood cell that is made in the bone marrow. It starts when the body makes too many white blood cells called histiocytes.

These clinical practice guidelines provide the latest evidence and expert-consensus for diagnosing and treating the three most common forms of histiocytosis in adults: Langerhans cell histiocytosis (LCH), Erdheim-Chester Disease (ECD,) and Rosai Dorfman Disease (RDD).

Histiocytosis is a generic name for a group of syndromes characterized by an abnormal increase in the number of certain immune cells called histiocytes. These include monocytes, macrophages, and dendritic cells.

Histiocytosis is a general name for a group of disorders or "syndromes" that involve an abnormal increase in the number of specialized white blood cells that are called histiocytes. Recently, new knowledge about this family of diseases has led experts to develop a new classification.

Adult histiocyte disorders are rare diseases. The most common of these is Langerhans cell histiocytosis (LCH), which affects only a few hundred patients every year in the United States. LCH results from the body's overproduction of immature histiocytes, which are a type of white blood immune cell.

What is a histiocytosis? A histiocytosis is a disease in which there are too many histiocyte cells in the skin and other organs. Normal histiocyte cells are part of the immune system, alerting infection-fighting cells to the presence of foreign material such as bacteria (antigen presentation).