Biliverdin (from the Latin for green bile) is a green tetrapyrrolic bile pigment, and is a product of heme catabolism. [1][2] It is the pigment responsible for a greenish color sometimes seen in bruises. [2] Biliverdin results from the breakdown of the …

2023年5月1日 · Biliverdin is a tetrapyrrolic, water-soluble compound formed by the breakdown of heme.[1] Heme is broken down into biliverdin and carbon monoxide and iron by heme oxidase. Biliverdin is then quickly broken down to bilirubin by biliverdin reductase.[2]

2022年12月8日 · Biliverdin is a green-coloured pigment found in the bile. During the breaking down of heme, biliverdin is formed as a byproduct. This biliverdin undergoes further breakdown through biliverdin reductase to form bilirubin. Bilirubin, upon oxidation, changes back to biliverdin.

Biliverdin is a linear tetrapyrrole produced in the reticuloendothelial system by the first step of heme degradation, catalysed by heme oxygenase. It has a role as a human metabolite and a mouse metabolite.

Biliverdin is a by-product of heme oxygenase and the substrate of biliverdin reductase. If the reductase is inhibited, biliverdin accumulates and green jaundice occurs. Biliverdin has shown in vitro beneficial roles in free radical-related diseases.

Biliverdin is a degradation product of hemoglobin and other heme proteins, formed when the heme residue of hemoglobin is enzymatically decomposed by heme oxygenase. It can be further reduced to bilirubin by biliverdin reductase. Biliverdin is involved in the liver's excretion of bile and is considered a marker of liver function.

2024年5月1日 · The meaning of BILIVERDIN is a green pigment that occurs in bile and is an intermediate in the degradation of hemoglobin heme groups to bilirubin.

a green bile pigment that is formed by catabolism of hemoglobin and converted to bilirubin in the liver. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

Biliverdin (BV) has emerged as a cytoprotective and important anti-inflammatory molecule. Conversion of BV to bilirubin (BR) is catalyzed by biliverdin reductase (BVR) and is required for the downstream signaling and nuclear localization of BVR.

2023年5月1日 · Biliverdin is a tetrapyrrolic, water-soluble compound formed by the breakdown of heme. Heme is broken down into biliverdin and carbon monoxide and iron by heme oxidase. Biliverdin is then quickly broken down to bilirubin by biliverdin reductase.