Von Willebrand factor (VWF) (German: [fɔn ˈvɪləbʁant]) is a blood glycoprotein that promotes primary hemostasis, specifically, platelet adhesion.

2023年2月20日 · Von Willebrand factor (vWF) is a glycoprotein crucial to primary hemostasis through platelet and subendothelial collagen adhesion and the intrinsic coagulation cascade through factor VIII stabilization.

2021年10月26日 · Von Willebrand disease is a lifelong bleeding disorder in which your blood doesn't clot properly. People with the disease have low levels of von Willebrand factor, a protein that helps blood clot, or the protein doesn't perform as it should.

2024年5月15日 · Von Willebrand disease (VWD) is a blood disorder in which the blood does not clot properly. Blood contains many proteins that help the blood clot when needed. One of these proteins is called von Willebrand factor (VWF). People with VWD either have a low level of VWF in their blood or the VWF protein doesn't work the way it should.

2023年8月28日 · Von Willebrand disease is a bleeding disorder caused by the qualitative or quantitative deficiency of the pro-von Willebrand factor. Affected people may complain of excessive bruising, prolonged bleeding from mucosal …

2024年6月28日 · Von Willebrand factor (vWF) mediates platelet adhesion to exposed subendothelial collagen at sites of vascular injury, facilitating the formation of primary hemostatic plugs. Von Willebrand disease (vWD), a bleeding disorder, arises …

2024年8月1日 · Von Willebrand factor (VWF) is a protein crucial to the blood clotting process. If you don’t have enough of this protein, or if it doesn’t work as it’s supposed to, you may have von...

In von Willebrand disease, genetic mutations affect your body’s ability to make normal von Willebrand factor. Factors are proteins that help your blood to clot. You have von Willebrand factor in your plasma , platelets and walls of your blood vessels .

Von Willebrand disease (VWD) is a hereditary quantitative deficiency or functional abnormality of von Willebrand factor, which causes platelet dysfunction. Bleeding tendency is usually mild. Screening tests usually show a normal platelet count and, possibly, a slightly prolonged partial thromboplastin time (PTT).

Von Willebrand factor, glycoprotein that plays an important role in stopping the escape of blood from vessels following vascular injury. Von Willebrand factor works by mediating the adherence of platelets to one another and to sites of vascular damage.