UGT2B7 (UDP-Glucuronosyltransferase-2B7) is a phase II metabolism isoenzyme found to be active in the liver, kidneys, epithelial cells of the lower gastrointestinal tract and also has been …

2024年12月25日 · UGT2B7 (UDP Glucuronosyltransferase Family 2 Member B7) is a Protein Coding gene. Diseases associated with UGT2B7 include Hepatocellular Adenoma and …

UDP-glucuronosyltransferases (UGTs) are phase II drug-metabolizing enzymes that metabolize endogenous fatty acids such as arachidonic acid metabolites, as well as many prescription …

UDP-glucuronosyltransferase 2B7 (UGT2B7) is one of the most significant isoforms of UGTs in human liver. This research measured UGT2B7 protein content and activities, including …

UGT2B7 polymorphisms may play a crucial role in the occurrence and development of breast cancer in the Han Chinese population; UGT2B7 could localize to the ER without any retention …

2020年2月12日 · One notable exception is the glucuronidation of morphine by the enzyme UGT2B7, which produces morphine-6-glucuronide with enhanced analgesic activity relative to …

UGT2B7. The uridine diphosphate-glucuronosyltransferase 2B7 (UGT2B7) enzyme is responsible for metabolizing morphine, codeine, and buprenorphine into its metabolites through …

2024年3月5日 · Title: The function of uterine UDP-glucuronosyltransferase 1A8 (UGT1A8) and UDP-glucuronosyltransferase 2B7 (UGT2B7) is involved in endometrial cancer based on …

The 1.8-Å resolution apo crystal structure of the UDP-glucuronic acid binding domain of human UGT2B7 (2B7CT) is the only structure of a mammalian UGT target determined to date. In this …

2003年3月10日 · We have screened a cohort of 239 Norwegian cancer patients for sequence variation in the coding and regulatory regions of the UDP-glucuronosyltransferase 2B7 gene …