2018年10月1日 · Toxic nodule or toxic multinodular goiter refers to one or more nodules (typically benign growths) in the thyroid gland that make thyroid hormone without responding to the signal to keep thyroid hormone balanced.

Toxic nodular goiter, or Plummer’s disease, is defined by an enlarged thyroid gland starting from a simple goiter. Resulting nodules produce too much thyroid hormone.

A toxic thyroid nodule refers to a single nodule in the thyroid gland that releases excessive thyroid hormones. The excess thyroid hormone production is termed ‘hyperthyroidism’ and can causes symptoms of thyrotoxicosis (i.e. due to excess thyroid hormones).

Toxic Multinodular Goiter: Multiple nodules with similar mutations in some nodules, others differ in function. Toxic Adenoma: Typically a single, autonomously functioning thyroid nodule. Patients usually >40 years old. Often have a long-standing multinodular goiter or single thyroid nodule.

Toxic nodular goiter involves an enlarged thyroid gland that contains a small rounded mass or masses called nodules, which produce too much thyroid hormone. Alternative Names: Toxic adenoma; Toxic multinodular goiter; Plummer's disease. Causes, incidence, and risk factors: Toxic nodular goiter arises from a long-standing simple goiter and ...

Toxic multinodular goiter (TMNG), also known as multinodular toxic goiter (MNTG), is an active multinodular goiter associated with hyperthyroidism.. It is a common cause of hyperthyroidism [2] [3] in which there is excess production of thyroid hormones from functionally autonomous thyroid nodules, which do not require stimulation from thyroid stimulating hormone (TSH).

2022年12月7日 · Toxic nodular goiter is a condition wherein one or more growths or nodules occur in the thyroid gland, making excess thyroid hormone which is released into the bloodstream, resulting in hyperthyroidism.

2021年2月8日 · A toxic thyroid nodule is an adenoma (toxic adenoma) or hyperplastic nodule observed on radionuclide scintigraphy that usually (but not always) causes hyperthyroidism. It develops most commonly as a result of a somatic mutation of the thyrotropin-stimulating hormone receptor or stimulatory G protein alpha subunit (Gs alpha).

Toxic nodular goiter involves an enlarged thyroid gland. The gland contains areas that have increased in size and formed nodules. One or more of these nodules produce too much thyroid hormone.

2022年10月26日 · Toxic multinodular goiter is most common in older patients. Onset of symptoms is more insidious and symptoms less dramatic than for Graves disease. Patients may have apathetic hyperthyroidism (minimal signs/symptoms) or subclinical hyperthyroidism (isolated thyroid-stimulating hormone suppression). Spontaneous remission is rare.