Susceptibility of a host depends on genetic or constitutional factors, specific immunity, and nonspecific factors that affect an individual’s ability to resist infection or to limit pathogenicity. An individual’s genetic makeup may either increase or decrease susceptibility.

2024年4月3日 · A person can become more susceptible to infection when: They have underlying medical conditions such as diabetes, cancer or organ transplantation. These can decrease the immune system's ability to fight infection.

2024年9月30日 · Evidence shows that men and women respond differently to infection because different parts of their immune systems are enhanced. Men have a more robust innate immune response, while women have more of what we call an adaptive and memory immune response.

In this essay, we consider the factors governing individual susceptibility and identify 11 attributes that affect the outcome of host-microbe interaction: microbiome, inoculum, sex, temperature, environment, age, chance, history, immunity, nutrition, and genetics.

Susceptibility to infection and many other human diseases (including diabetes and ischaemic heart disease) arises from the complex interaction of environmental and host genetic factors.

Susceptibility refers to the ability of an exposed individual (or group of individuals) to resist infection or limit disease as a result of their biological makeup. Factors influencing susceptibility include both innate, genetic factors and acquired factors such as the specific immunity that develops following exposure or vaccination.

2012年2月7日 · Genome-wide association studies have identified various strong associations between genetic polymorphisms and susceptibility to common infectious disease phenotypes, such as HIV-1, hepatitis B...

23 小时之前 · Transmission risk and infection or susceptibility risk are related. While susceptibility risk is broader and includes factors like age and prior immunity, this review focuses on the aspects ...

2023年6月21日 · One would be genetic susceptibility: you’re born with a genetic predisposition to becoming infected more easily. You could have inborn errors, such as poly­morphisms in genes that are well...

2025年1月6日 · For an optimized understanding of infection susceptibility in otherwise healthy children, it is important to consider risk factors such as environmental and social circumstances, which have been implicated in the recurrence of respiratory infections that constitute the majority of infections in childhood. 8-10 To investigate whether the burden ...