This review will describe current understanding of the immunopathogenesis and pathophysiology of anaphylaxis, focusing on the roles of IgE and IgG antibodies, immune effector cells, and mediators thought to contribute to examples of the disorder.

2017年5月9日 · This review will describe current understanding of the immunopathogenesis and pathophysiology of anaphylaxis, focusing on the roles of IgE and IgG antibodies, immune effector cells, and mediators thought to contribute to examples of the disorder.

2023年1月26日 · Anaphylaxis is an acute, life-threatening hypersensitivity disorder defined as a generalized, rapidly evolving, multi-systemic allergic reaction. Anaphylactic reactions were classified as IgE-mediated responses, while anaphylactoid reactions were classified as IgE-independent events.

2024年3月6日 · The pathophysiology of anaphylaxis will be reviewed here. The clinical manifestations, diagnosis, and management of anaphylaxis and the epidemiology and etiology of fatal anaphylaxis are discussed separately. (See "Anaphylaxis: Emergency treatment" and …

These overlapping and synergistic physiological effects contribute to the overall pathophysiology of anaphylaxis that variably presents with generalized urticaria and angioedema, bronchospasm, and other respiratory symptoms, hypotension, syncope, and other cardiovascular symptoms, and nausea, cramping, and other gastrointestinal symptoms.

This review will describe current understanding of the immunopathogenesis and pathophysiology of anaphylaxis, focusing on the roles of IgE and IgG antibodies, immune effector cells, and mediators thought to contribute to examples of the disorder.

Recent advances in pathophysiology have delineated novel etiologies, including mast cell activation disorders, hereditary hyper-tryptasemia, hormone sensitivity syndromes (including catamenial anaphylaxis) and allergy to alpha-gal that need to …

This review will describe current understanding of the immunopathogenesis and pathophysiology of anaphylaxis, focusing on the roles of IgE and IgG antibodies, immune effector cells, and mediators thought to contribute to examples of the disorder.

2019年12月11日 · To understand the pathophysiology of anaphylaxis, recognition of how intracellular mechanisms cause mediator release is a vital step. It is through these intracellular signalling pathways that mast cells are able to degranulate at such speed, and arachidonic acid pathways to adapt to the production of lipid-based mediator substances, and the ...

2017年8月1日 · This review will describe current understanding of the immunopathogenesis and pathophysiology of anaphylaxis, focusing on the roles of IgE and IgG antibodies, immune effector cells, and mediators thought to contribute to examples of the disorder.