Panniculitis with systemic features. Associated symptoms of fever, malaise and arthralgia are common in patients with panniculitis. When these are prominent, diagnoses to consider include: Cutaneous vasculitis; Infective panniculitis; Subcutaneous acute febrile neutrophilic dermatosis; Panniculitis associated with pancreatic disease

The term 'nodular panniculitis' is used when no specific cause for the panniculitis has been found (such as erythema nodosum or alpha-1-antitrypsin deficiency). Nodular panniculitis is also referred to as relapsing, febrile, non-suppurative panniculitis. In the past, it was also called Weber Christian disease. Who gets nodular panniculitis?

Bacterial panniculitis can appear in immunocompetent as well as immunosuppressed individuals. It can develop as a result of direct inoculation or from seeding from systemic infection. The classical histopathological appearance is a lobular or mixed lobular/septal suppurative panniculitis with heavy infiltrate of neutrophils.

Panniculitis is diagnosed and classified by a combination of clinical features and skin biopsy findings. In up to 40% of cases of pancreatic panniculitis, skin lesions are the presenting feature of pancreatic disease. The association of panniculitis with a pancreatic tumour may be recognised by the Schmid triad: Eosinophilia; Panniculitis ...

Panniculitis Associated With Severe a1-Antitrypsin Deficiency: Treatment and Review of the Literature. Archives of Dermatology. 1987 Dec 1;123(12):1655-61. PubMed; Pinto AR, Maciel LS, Carneiro F, Resende C, Chaves FC, Freitas AF. Systemic nodular panniculitis in a patient with alpha‐1 antitrypsin deficiency (PiSS phenotype).

2018年6月27日 · Eosinophilic panniculitis; Rheumatoid nodule. Nodules due to predominantly lobular panniculitis include: Connective tissue disease (eg, panniculitis associated with cutaneous lupus erythematosus) Erythema nodosum leprosum (type 2 lepra reaction due to leprosy) Pancreatic panniculitis in which subcutaneous nodules may become ulcerated or fluctuant.

Panniculitis is characterised by red, firm, tender plaques or nodules that have a predilection for the lower legs. The most common form of panniculitis is erythema nodosum , which can be distinguished from cellulitis by its bilateral and multifocal distribution, recurrent nature, and absence of oedema.

Histology of subcutaneous panniculitis-like T-cell lymphoma. Scanning power view demonstrates lobular panniculitis (Figure 1). Relatively little dermal or epidermal involvement is seen (Figure 2). A dense infiltrate is seen predominantly within the fat lobules while some spillover into the septal panniculus may be seen (Figure 3). Germinal ...

Cytophagic histiocytic panniculitis is usually lethal if untreated. Symptomatic treatment consists of transfusion and corticosteroid therapy. Etoposide and ciclosporin have been reported to be helpful in some cases. Some authors recommend that cytophagic histiocytic panniculitis should be treated with CHOP-like polychemotherapy.

Poststeroid panniculitis is a rare complication of systemic corticosteroid therapy. Clinically, erythematous nodules and indurated plaques develop on the cheeks of children within days or weeks following rapid systemic steroid tapering or cessation. Histology of poststeroid panniculitis