PLGA, PLG, or poly(lactic-co-glycolic) acid (CAS: 26780-50-7) is a copolymer which is used in a host of Food and Drug Administration (FDA) approved therapeutic devices, owing to its biodegradability and biocompatibility. [1]

Poly(lactic-co-glycolic) acid (PLGA) has attracted considerable interest as a base material for biomedical applications due to its: (i) biocompatibility; (ii) tailored biodegradation rate (depending on the molecular weight and copolymer ratio); ...

PLGA is biocompatible and biodegradable, exhibits a wide range of erosion times, has tunable mechanical properties and most importantly, is a FDA approved polymer.

2014年2月28日 · This paper critically reviews the scientific challenge of manufacturing PLGA-based materials with suitable properties and shapes for specific biomedical applications, with special emphasis on bone tissue engineering.

Poly-lactic-co-glycolic acid (PLGA) has been the most successful polymeric biomaterial for use in controlled drug delivery systems. There are several different chemical and physical properties of PLGA that impact the release behavior of drugs from ...

2023年1月1日 · Poly (lactic-co-glycolic acid) (PLGA) is a biodegradable polymer with a lot of potential in pharmaceutical nanotechnology and novel drug carrier systems due to its superior properties. PLGA is noted for its biocompatibility and biodegradability when hydrolytically degraded into nontoxic compounds, glycolic acid, and lactic acid via natural ...

Polylactic-co-glycolic acid (PLGA) is one of the extensively researched synthetic biodegradable polymers due to its favorable properties. It is also known as a 'Smart Polymer' due to its stimuli sensitive behavior.

2012年7月20日 · This review presents why PLGA has been chosen to design nanoparticles as drug delivery systems in various biomedical applications such as vaccination, cancer, inflammation and other diseases.

2012年7月20日 · PLGA nanoparticles are described in the literature as effective nanocarriers for the encapsulation of various anti-cancer agents such as paclitaxel [19], 9-nitrocamptothecin [20], cisplatin [21], etc. but also for the encapsulation of various drugs such as haloperidol [22], estradiol [23], etc.

2011年6月20日 · In past two decades poly lactic-co-glycolic acid (PLGA) has been among the most attractive polymeric candidates used to fabricate devices for drug delivery and tissue engineering applications.