A neurodegenerative disease is caused by the progressive loss of neurons, in the process known as neurodegeneration. [2] [3] Neuronal damage may also ultimately result in their death.

Neurodegenerative disorders are chronic conditions that damage and destroy parts of your nervous system over time, especially your brain. These conditions are permanent and incurable, but many are now treatable thanks to medical advances.

2022年8月12日 · The term "neurodegeneration" can be applied to several conditions that result in the loss of nerve structure and function.

Although neurons are not immortal, the progressive loss of neurons, neuron structure, and/or their functions, known as neurodegeneration, is central to the pathophysiology of several brain disorders and is also a major health concern.

Neurodegeneration is an umbrella term used to describe various pathological processes occurring in the central nervous system (CNS) that result in progressive structural and functional deficits and ultimately the death of neuronal cells [5].

Neurodegeneration involves complex interactions between adjacent cells and their axonal projections; neurons have both proximal and distal regions that have distinct cellular environments and in turn distinct mechanisms of disease pathology.

2013年12月12日 · Neurodegeneration: Exploring Commonalities Across Diseases: Workshop Summary. Show details

2021年12月8日 · Neurodegeneration with Brain Iron Accumulation (National Institute of Neurological Disorders and Stroke) Neuronal Ceroid Lipofuscinosis (Batten Disease) (National Institute of Neurological Disorders and Stroke) Prion Diseases (National Institute of Allergy and Infectious Diseases)

Neurodegeneration is a feature of many debilitating, incurable diseases that are rapidly rising in prevalence, such as Parkinson's disease. There is an urgent need to develop new and more effective therapeutic strategies to combat these devastating diseases.

2023年8月26日 · Neurodegeneration is a progressive and irreversible process of structural and/or functional loss in neuronal cells, which affects vulnerable cell subsets in certain anatomic brain regions leading to various neurodegenerative diseases.