2018年11月30日 · Many therapeutic agents have been associated with thrombocytopenia. Although in most cases, drug-induced thrombocytopenia is associated with bleeding, life-threatening thromboembolic complications are common in patients with heparin-induced thrombocytopenia (HIT).

2024年5月1日 · Drugs can cause thrombocytopenia by several mechanisms including direct bone marrow or other organ toxicity. Many of the cytotoxic drugs used for cancer chemotherapy and other conditions produce dose-dependent reductions in platelet counts due to bone marrow suppression as a known effect of the drug.

2022年8月25日 · Identifying drugs that cause acute thrombocytopenia: an analysis using 3 distinct methods.

2023年4月18日 · Drug-induced thrombocytopenia occurs when certain medicines destroy platelets or interfere with the body's ability to make enough of them. There are two types of drug-induced thrombocytopenia: immune and nonimmune.

2024年3月1日 · Some medications can cause a low platelet count, which can lead to excessive bleeding. Heparin is the most frequent cause, but common drugs like acetaminophen and some antibiotics can also...

2023年11月16日 · Did you know that certain medications can cause symptom of 'Thrombocytopenia'. Find these drugs listed on the page and be warned of similar symptoms as possible side-effects.

Hundreds of drugs have been implicated in its pathogenesis, among those, drugs most often associated with DITP are: heparin, cinchona alkaloid derivatives (quinine and quinidine), penicillin, sulfonamides, non-steroidal anti-inflammatory drugs (NSAIDs), anticonvulsants, antirheumatic and oral antidiabetic drugs, gold salts, diuretics ...

2010年9月23日 · To provide a resource for diagnosis of DITP and for drug safety surveillance, we analyzed 3 distinct methods for identifying drugs that may cause thrombocytopenia.

2024年9月26日 · Drugs that may cause thrombocytopenia include heparin, acetaminophen, and some chemotherapy medications. Learn more about drug-induced thrombocytopenia.

Most cases of drug-induced thrombocytopenia (DITP) are caused by drug-dependent antibodies that are specific for the drug structure and bind tightly to platelets by their Fab regions but only in the presence of the drug.