Kaempferol is a flavonol under the category of flavonoids, and is widely distributed in different plant genera such as Delphinium, Camellia, Berberis, Citrus, etc. Kaempferol has a beneficial role on different inflammatory-related diseases such as cardiovascular, cancers, and neurodegenerative diseases. The antiinflammatory actions of ...

2013年6月15日 · Therefore, kaempferol could possibly be combined with another substance with an even higher affinity for Abcg2, which would leave kaempferol inside to wreak havoc on the malignant cells. In addition, kaempferol has been found to lower mRNA levels of ABCC6, another ATP-binding cassette transporter ( Luo et al., 2010 ).

2021年12月1日 · Kaempferol have obvious effects on extension of dendrites, transport of melanosomes from perinuclear to cell tips coping with SK-MEL-28 cells through F-actin or HMB45 staining and mediates hyperpigmentation in B16F10 cells by stimulating melanosome maturation. a and b) Kaempferol (15 μM) treated with B16F10 cells for 72 h, compared with Ctrl ...

2024年11月17日 · Kaempferol is widely distributed in a variety of common fruits, vegetables and Chinese herbal medicine [8]. Clinical research have showed that kaempferol has widely biological activities, containing anti-inflammation, anti-oxidation, …

Kaempferol is a flavonoid with many activities such as neuroprotective activity, anti-oxidant activity, and anti-inflammatory activity [231]. Kaempferol enhances mitochondrial anti-oxidant activity thus inducing autophagy in the rotenone-induced PD model [232]. It showed a neuroprotective effect in MPTP induced PD model [233]. Nanokaempferol of ...

2024年11月5日 · Kaempferol (KAE) is a natural flavonoid mainly derived from the rhizome of Kaempferia galanga L., but is also found in food plants such as broccoli, tomatoes, strawberries, grapes and beans [1], [2]. Epidemiological data suggested that consumption of foods containing KAE protected against myocardial diseases and lowered the risk of acute ...

2025年1月13日 · A, the effects of Kaempferol on α2M levels in PC-3 cells and in co-culture models, (∗∗∗P < 0.001); B, the effects of Kaempferol on migration in PC-3 cells; C, the effects of Kaempferol on invasion in PC-3 cells (magnification: × 200); D, the effects of Kaempferol on migration related protein in PC-3 cells; E, photographs were taken at 0 ...

2024年11月15日 · Kaempferol (KPF), a natural flavonoid, has anti-inflammatory properties, though its mechanism in treating HUA combined with GA remains unclear. This study used a mouse model of HUA combined with GA and in vitro models with HK-2 and THP-1 …

2021年3月1日 · Kaempferol can ameliorate the lipopolysaccharide-induced production of the inflammatory mediators thymic stromal lymphopoietin, IL-1β, TNF-α, IL-8, and nitric oxide of macrophage-like cells differentiated by IL-32 (Nam et al., 2017) and protect against gamma radiation-induced mortality and damage by inhibiting oxidative stress and modulating ...

Kaempferol, a kind of flavonol, is derived from the rhizome of Kaempferia galanga, which is used in traditional medicine in Asia for hypertension, abdominal pain, headaches, and rheumatism. Recently, the impending role of kaempferol in the management of bone metabolism disorders such as osteoarthritis was explored in MC3T3-E1 cells.