Anticholinergic bronchodilators (or muscarinic receptor antagonists) block the parasympathetic nerve reflexes that cause the airways to constrict, so allow the air passages to remain open. Muscarinic receptor antagonists bind to muscarinic receptors and …

Inhaled anticholinergics are medications used to dilate and decongest the bronchial passages in patients with chronic obstructive pulmonary disease (COPD). Anticholinergics block the activity of acetylcholine, a neurotransmitter that nerve endings secrete to make muscles contract.

Overview/Summary: The inhaled anticholinergics (anticholinergics) are a class of bronchodilators primarily used in the management of chronic obstructive pulmonary disease (COPD), a condition characterized by progressive airflow restrictions that are not fully reversible. 1-3 Symptoms associated with

2025年2月4日 · Anticholinergic bronchodilators play a crucial role in managing respiratory conditions such as chronic obstructive pulmonary disease (COPD) and asthma. These medications work by relaxing the airway muscles, reducing bronchoconstriction, and making breathing easier.

2022年8月9日 · Anticholinergics. Anticholinergics are available as ipratropium bromide (Atrovent®) and tiotropium bromide (Spiriva Respimat®). They block the effects of acetylcholine. Acetylcholine is a neurotransmitter that your body makes. Ipratropium bromide is available as an inhaler and a nebulizer solution.

Multiple randomized clinical trials show safety and efficacy of the newer long-acting inhaled anticholinergics, including tiotropium and aclidinium. A recent meta-analysis of tiotropium delivered with Respimat ® raised some safety concerns.

Respiratory anticholinergics are orally inhaled in the form of powders, aerosolized tiny particles or droplets, or solutions nebulized into a fine mist. Many types of inhalation devices such as metered dose inhalers and nebulizers are available.

This article reviews the most current evidence for inhaled anticholinergics in obstructive airway disease and summarizes outcomes reported in randomized controlled trials.

2024年11月15日 · Inhaled anticholinergics are used to treat chronic obstructive pulmonary disease (COPD), bronchitis, emphysema, asthma, and allergies. How do inhaled anticholinergics work? Inhaled anticholinergics block the parasympathetic nerve reflexes that cause the airways to constrict, resulting in bronchodilation (relaxation of the airways).

2024年5月3日 · Anticholinergic inhaled medicines include: Aclidinium (Tudorza Pressair) Glycopyrronium (Seebri Breezhaler) Tiotropium (Spiriva) Umeclidinium (Incruse Ellipta) Revefenacin (Yupelri) is a long acting nebulized medicine; Use your anticholinergic inhalers every day, even if you do not have symptoms.