In cell biology, focal adhesions (also cell–matrix adhesions or FAs) are large macromolecular assemblies through which mechanical force and regulatory signals are transmitted between …

Focal adhesion和EMT，肿瘤侵袭研究的卧龙凤雏，咱们就看一看怎么应用到自己的研究当中。 引起EMT的因素有很多，在肿瘤侵袭的研究中EMT基本上是都要出现的。

One of the earliest and perhaps best-characterized cell-ECM adhesion structures is focal adhesion, which represents strong ECM adhesion structures that are often found in adherent …

By responding to chemical and mechanical cues several allosterically regulated proteins create a dynamic multifunctional protein network that provides both adhesion to the extracellular matrix …

2012年2月1日 · The study of focal adhesion formation and assembly requires bringing integrin-receptor expressing cells in contact with extracellular matrix. As focal adhesions form in …

Focal adhesions lie at the convergence of integrin adhesion, signaling and the actin cytoskeleton. Cells modify focal adhesions in response to changes in the molecular composition, two …

Focal adhesions are specialized sites within the cell where clustered integrin receptors interact with the extracellular matrix on the outside of cells and with the actin cytoskeleton on the …

2019年1月2日 · Focal adhesions are large structures through which integrins and scaffold proteins link the actin cytoskeleton to the extracellular matrix.

2021年9月1日 · The major integrin adhesion complexes (IACs) characterised are focal adhesions (FAs), invadosomes (podosomes and invadopodia), hemidesmosomes (HDs) and reticular …

焦点粘附（Focal adhesion）是细胞与外部基质之间的一个重要连接点，它由多个蛋白质组成，包括整合素、钙蛋白、肌动蛋白等。 焦点粘附的形成和稳定对于细胞凋亡、增殖、迁移、分化 …