In biochemistry, denaturation is a process in which proteins or nucleic acids lose folded structure present in their native state due to various factors, including application of some external stress or compound, such as a strong acid or base, a concentrated inorganic salt, an organic solvent (e.g., alcohol or chloroform), agitation and radiatio...

2025年1月20日 · denaturation, in biology, process modifying the molecular structure of a protein or nucleic acid. Denaturation involves the breaking of many of the weak linkages, or noncovalent bonds, such as hydrogen bonds and hydrophobic interactions, within …

2016年12月17日 · Denaturing a biological molecule refers to the loss of its three-dimensional (3-D) structure. Since molecules like proteins and DNA depend on their structure to accomplish their function, denaturation is accompanied by a loss of function.

2024年2月6日 · Denaturation is the process of breaking many of the weak bonds, such as hydrogen bonds, that give proteins their highly ordered structure when they are in their native, natural state. Weak and irregularly arranged, denatured proteins are mostly insoluble.

2024年10月29日 · In food science, denaturation is a desirable process, as seen in the cooking of eggs, where heat causes the proteins to coagulate, transforming the egg from a liquid to a solid state. In laboratory settings, researchers often exploit denaturation to …

2025年1月14日 · When a solution of a protein is boiled, the protein frequently becomes insoluble—i.e., it is denatured—and remains insoluble even when the solution is cooled. The denaturation of the proteins of egg white by heat—as when boiling an egg—is an example of irreversible denaturation.

2022年6月16日 · In biochemistry, denaturation is defined as a process in which a molecular structure deviates from its original state when exposed to a denaturing agent. In biology, examples of biomolecules that denature are proteins and nucleic acids (e.g. DNA).

For most proteins, denaturation is a complex process involving transient intermediates in several reversible and eventually irreversible steps.

Protein denaturation is the deformation of a protein’s shape through some external stress. The external stress can be due to extremes of physical (heat, radiation etc.) or chemical agents (acids, alkalies etc.). Denaturation in proteins is simply the unfolding of proteins due to the breakage of the bonds holding them.

: to modify the molecular structure of (something, such as a protein or DNA) especially by heat, acid, alkali, or ultraviolet radiation so as to destroy or diminish some of the original properties and especially the specific biological activity. Recent Examples on the Web.