2023年7月31日 · Skin lesions are frequently a sentinel for disseminated disease; however, primary cutaneous lesions do occur in immunocompetent persons. The primary cutaneous lesion may be a papule, maculopapular lesion with an ulcerated center or a violaceous nodular lesion.

In immunosuppressed patients, especially those with HIV infection or AIDS, skin infection is usually a sign of disseminated disease. Skin infection presents as: Papules, pustules, nodules and ulcers; Bleeding into the skin, presenting as petechiae or ecchymoses. How is …

We report four cases of systemic cryptococcosis with varied cutaneous presentations, including a bacterial cellulitis-like lesion, in renal transplant patients, showing the many forms of this infrequent infection in the skin and the importance of the dermatologist for their identification.

Cutaneous infections are the third most common clinical manifestations of cryptococcosis and patients can present with a variety of skin lesions. Lesions are often indistinguishable from those owing to other infections; as such, a skin biopsy with culture and histopathology are absolutely essential for definitive diagnosis.

Atypical skin lesions observed in immunosuppressed patients can be the first symptoms of C. neoformans infection, therefore cryptococcosis should always be a part of differential diagnosis in such cases and raise physicians’ awareness.

2023年12月20日 · Lesions may have variable appearance (e.g., papular lesions that may become pedunculated, plaques, ulcers, abscesses, pustules, or nodules.) Skin lesions usually reflect hematogenous dissemination, but may occasionally represent the primary site of infection following cutaneous inoculation.

2019年3月13日 · In patients with human immunodeficiency virus (HIV) disease, cutaneous cryptococcosis can be indistinguishable from mollluscum contagiosum; the skin lesions appear as skin-colored papules with central umbilication (Figure 1).