Receptor-mediated endocytosis (RME), also called clathrin-mediated endocytosis, is a process by which cells absorb metabolites, hormones, proteins – and in some cases viruses – by the inward budding of the plasma membrane (invagination).

2018年2月7日 · Abstract | Clathrin-mediated endocytosis is a key process in vesicular trafficking that transports a wide range of cargo molecules from the cell surface to the interior. Clathrin-mediated...

2023年11月30日 · Clathrin-mediated endocytosis (CME) is a vesicular transport event that facilitates the internalization and recycling of receptors engaged in a variety of processes, including signal transduction (G-protein and tyrosine kinase receptors), nutrient uptake and synaptic vesicle reformation [1].

Clathrin mediated endocytosis (CME) is ubiquitous process in all eukaryotic cells. It is the major mechanism for sorting and internalisation of various macromolecules, proteins and lipids and controlling signalling pathway activation.

2018年2月5日 · Clathrin-mediated endocytosis, a type of endocytosis that capitalizes on the clathrin coat, a number of adaptor and accessory proteins, and the GTPase dynamin, is well understood, while the contributions of clathrin-independent fast endocytosis, kiss-and-run, bulk endocytosis and ultrafast endocytosis are still being evaluated.

2011年7月1日 · Calnexin-deficient cells have enhanced clathrin-dependent endocytosis in neuronal cells and mouse neuronal system. This is reversed by expression of full length calnexin or calnexin C-tail.

2020年8月4日 · Clathrin-dependent endocytosis is the best studied of the two and is defined by the presence of a clathrin coat on the endocytic vesicle. Clathrin-independent endocytosis represents multiple, less defined internalization pathways.

Abstract | Clathrin-mediated endocytosis is the endocytic portal into cells through which cargo is packaged into vesicles with the aid of a clathrin coat. It is fundamental to...

2013年1月1日 · Clathrin-mediated endocytosis (CME) is an evolutionary conserved pathway that is the main and best characterized pathway of endocytosis, although several clathrin-independent endocytosis pathways have also been described [1, 2].

2011年3月22日 · The molecular dynamics of clathrin-mediated endocytosis in living cells has been mapped with an approximately ten-fold improvement in temporal accuracy, yielding new insights into the molecular mechanism.