Open links in new tab
  1. Copilot Answer
    LocationCartilage
    FunctionProduce and maintain cartilage matrix
    Latinchondrocytus
    Development

    From least- to terminally-differentiated, the chondrocytic lineage is:
    1. Colony-forming unit-fibroblast
    2. Mesenchymal stem cell / marrow stromal cell… See more

    Structure

    The chondrocyte in cartilage matrix has rounded or polygonal structure. The exception occurs at tissue boundaries, for example the articular surfaces of joints, in which chondrocytes may be flattened or discoid. Intr… See more

    Genetics

    The number of chondrocyte cells created and their maturation process can be influenced by multiple different genes and proteins. Two proteins, bone morphogenetic protein 4(BMP-4) and fibroblast growth factor 2(FGF2) … See more

    Chondrocyte Primary Culture

    Chondrocytes can be prepared by sequential enzymatic digestion of cartilage with Pronase and Collagenase and cultured in DMEM-F12 cell culture media. See more