2020年8月18日 · As @MaxW already pointed out, 1:4 means that you have to use four times as much water as t-BuOH. But I also want to explain why this is, because you'll probably see this …

2019年8月13日 · Several reasons: t-BuOK is especially known as a strong base, and a poor nucleophile. Its large, bulky structure causes it to perform exceptionally poorly in substitution, …

2018年2月19日 · Based on the observation that the dianion of anthracene is more basic than its radical anion, 2 the authors designed an experiment utilizing 2% d 1-t-BuOH as the alcohol …

2015年5月1日 · The short answer is that the steric hindrance of the tert butyl alcohol makes it hard to add an protonate the hydroxy group.

2019年9月28日 · 1-chloro-2-methylpropane --> 2-chloro-2-methylpropane. My understanding is that an E2 reaction produces two types of alkenes, the major product for non-sterically …

2018年2月6日 · Stack Exchange Network. Stack Exchange network consists of 183 Q&A communities including Stack Overflow, the largest, most trusted online community for …

2017年4月27日 · Can Tert-butoxide displace bromide via SN2 reaction? I read that Tert-butoxide is bulky and has steric hindrance, even with primary substrates. How is this reaction (picture …

$\begingroup$ You are assuming that the phenol and alcohol are in water. In a less polar solvent I suspect no or very little dissociation of phenol occurs, thus the polar nature of the solvent has …

2017年1月9日 · Stack Exchange Network. Stack Exchange network consists of 183 Q&A communities including Stack Overflow, the largest, most trusted online community for …

2018年2月18日 · Why not E2? The E2 mechanism follows an "anti-periplanar orientation of hydrogen and leaving group". Suppose the reactant's stereochemistry is such that there is no …