Lawn et al. (1981) identified the IFNA14 gene, which they designated LEIF2H. The deduced protein contains 189 amino acids. Lawn et al. (1981) determined that the coding region of the IFNA14 gene is contained within a single exon. The 5 …

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3448 230396 Ensembl ENSG00000228083 ENSMUSG00000063376 UniProt P01570 Q80SU4 RefSeq (mRNA) NM_002172 NM_177347 RefSeq (protein) NP_002163 NP_796321 Location (UCSC) Chr 9: 21.24 – 21.24 Mb Chr 4: 88.56 – 88.56 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interferon alpha-14 is a protein that in humans is encoded by the IFNA14 gene. References ^ a b c GRCh38: Ensembl release 89 ...

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本品适用于既往经表皮生长因子受体 (EGFR)酪氨酸激酶抑制剂 (TKI）治疗时或治疗后出现疾病进展，并且经检测确认存在 EGFR T790M 突变阳性的局部晚期或转移性非小细胞性肺癌 (NSCLC)成人患者的治疗。 该适应症是基于一项包括 220 例不可手术切除的局部晚期或转移性、经第/第二代 EGFR TKI 治疗后进展并伴有 EGFR T790M 突变阳性、或原发性 EGFR T790M 突变 NSCLC 阳性患者的Ⅱb 临床试验的结果给予的附条件批准。 该适应症的完全批准将取决于正在进行的确证 …

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