2016年11月1日 · Topical antifungal agents are effective in treating onychomycosis, with a number needed to treat (NNT) of 7 to 17. (Strength of Recommendation: A, based on consistent findings from good-quality...

Topical therapy, including ciclopirox 8%, efinaconazole 10%, and tavaborole 5%, is less effective than oral agents but can be used to treat mild to moderate onychomycosis, with...

2022年9月8日 · Therapeutic options for onychomycosis include oral antifungal medications, topical antifungal medications, and physical interventions. Factors such as the causative organism, severity of nail involvement, treatment side effects, and patient preference influence treatment selection.

Fungal infections of the toenails, causing thickening, roughness, and splitting, often caused by Trichophyton rubrum or T. mentagrophytes, Candida, and occasionally molds. The medications listed below are related to or used in the treatment of this condition. Activity ? What home remedies work well for toenail fungus?

Novel broad spectrum topical antifungal agents that have shown promising results in the treatment of onychomycosis include tazarotene (Tazorac), lanoconazole (Astat), luliconazole (Luzu, Luzam, Lulicon), NCV-422, and ME1111 [53, 66].

2021年2月1日 · Topical antifungal drugs, including efinaconazole 10% solution (Jublia), tavaborole 5% solution (Kerydin), and ciclopirox 8% lacquer and hydrolacquer, are beneficial...

Onychomycosis may cause pain, psychosocial problems, and secondary infections, therefore meriting treatment. This review describes the range of treatment modalities, including FDA-approved systemic drugs and topical therapies. Additionally, new and emerging oral and topical therapies are discussed.

Efinaconazole 10% solution and tavaborole 5% solution are new topical antifungals specifically developed for the treatment of dermatophyte onychomycosis. In Phase 3 clinical trials, both newer agents were applied once daily for 48 weeks without concomitant nail debridement.

Decision Tree on Therapeutic Recommendations for the Treatment of Confirmed Onychomycosis. These are topline recommendations for treatment.

2024年5月15日 · Treatment. Treatment for toenail fungus isn't always needed. And sometimes self-care and nonprescription products clear up the infection. Talk with your health care provider if your condition doesn't improve. Treatment depends on the severity of your condition and the type of fungus causing it. It can take months to see results.