2017年3月15日 · Patients may present with bone pain or with symptoms that are often nonspecific, such as nausea, vomiting, malaise, weakness, recurrent infections, and weight loss....

2023年1月30日 · This activity reviews the underlying cause, presentation, diagnosis, and treatment of multiple myeloma. The importance of early recognition, treatment, and an interprofessional approach is highlighted in this activity.

2016年1月11日 · Multiple myeloma is a cancer of plasma cells that results in overproduction of abnormal antibodies in the bone marrow. It commonly causes bone pain, fractures, anemia, and kidney problems. Risk factors include age over 60 and exposure to chemicals like pesticides, radiation, or certain industrial chemicals.

2024年11月2日 · Presenting signs and symptoms of multiple myeloma (MM) include bone pain, pathologic fractures, weakness, anemia, infection (often pneumococcal), hypercalcemia, spinal cord compression, and...

2024年3月26日 · clinical presentation of multiple myeloma Signs or symptoms related to the infiltration of plasma cells into the bone or other organs or to kidney damage from excess light chains:

2008年10月1日 · Multiple myeloma, the most common bone malignancy, is occurring with increasing frequency in older persons. Typical symptoms are bone pain, malaise, anemia, renal insufficiency, and...

Patients may present with bone pain or with symptoms that are often nonspecific, such as nausea, vomiting, malaise, weakness, recurrent infections, and weight loss. Many...

Multiple myeloma can present with a wide constellation of symptoms including hypercalcaemia, anaemia, renal impairment and/or bony pain. A combination of these symptoms, particularly if unexpected or unexplained, should prompt diagnostic evaluation for myeloma.

The acute presentation of multiple myeloma can be devastating and carries a relatively high early mortality rate. Early indicators of the presence of multiple myeloma include anemia (73%), bone pain (58%), elevated creatinine (48%), and generalized fatigue (32%) [ 1 ].

2018年12月18日 · Key points include: - Multiple myeloma is a neoplastic proliferation of plasma cells producing monoclonal immunoglobulins that can cause symptoms. - It occurs more commonly in older adults, blacks, and those with radiation/chemical exposure. Common signs are anemia, bone pain, elevated creatinine, and hypercalcemia.