High-grade B-cell lymphoma (HGBCL): This type of B-cell lymphoma causes the same symptoms as DLBCL and Burkitt lymphoma. There are treatments that put the condition into remission, but it often comes back.

High-grade B-cell lymphoma (HGBCL, previously known as double-hit lymphoma) is an aggressive type of B-cell non-Hodgkin lymphoma (NHL) characterized by rearrangements (parts of genes switch places within chromosomes) in two particular genes.

2022年9月1日 · High-grade B-cell lymphoma (HGBL), not otherwise specified (NOS), is a recently introduced diagnostic category for aggressive B-cell lymphomas. It includes tumors with Burkitt-like or blastoid morphology that do not have double-hit cytogenetics and that cannot be classified as other well-defined lymphoma subtypes.

2017年1月19日 · High-grade B-cell lymphomas (HGBLs) with MYC and BCL2 and/or BCL6 rearrangements, so-called “double-hit” lymphomas (HGBL-DH), are aggressive lymphomas that form a separate provisional entity in the 2016 revised World Health Organization Classification of Lymphoid Tumors.

High-grade B-cell lymphoma (HGBL) is a new category of B-cell non-Hodgkin lymphoma (NHL) introduced in 2008 by the World Health Organization (WHO). This type of lymphoma is aggressive (fast-growing) and can be grouped in two subtypes: Diffuse large B-cell lymphoma/high grade B-cell lymphoma with MYC and BCL2 rearrangements (DLBCL/HGBL-MYC/BCL2).

2023年10月25日 · In this multi-institutional retrospective study, we examined the characteristics and outcomes of 160 patients with high-grade B-cell lymphoma, not otherwise specified (HGBL-NOS)—a rare category defined by high-grade morphologic features and lack of MYC rearrangements with BCL2 and/or BCL6 rearrangements ("double hit").

There are different types of B cell and T cell lymphomas. Some of these are low grade, and some are high grade. In the UK, B cell lymphomas are more common than T cell or NK cell lymphomas. The most common types of high grade NHL are: Rarer types of high grade NHL include: Other rare types of high grade lymphomas include:

2021年8月5日 · CD10 and BCL6 coexpression suggests a follicular center cell derivation. The differential diagnosis includes diffuse large B cell lymphoma, NOS and so called double hit lymphoma. Additional materials have been sent for FISH analysis, the results of which will be reported separately and in an addendum.

High-grade B-cell lymphoma is a type of non-Hodgkin lymphoma (NHL). It may also be called double-hit or triple-hit lymphoma. Treatments include chemotherapy, stem cell transplant, targeted therapy, immunotherapy and radiation therapy.

phoma/high grade B-cell lymphoma with MYC and BCL2 rearrangements (DLBCL/HGBL-MYC/BCL2). This subtype is characterized by permanent changes (mutations) called transloca. ions in the parts of the DNA that contain the information for the MYC and BCL2 . roteins. This category includes most.