In the present study, we investigated the nature of the interplay between ferroptosis and other forms of cell death such as apoptosis. Human pancreatic cancer PANC-1 and BxPC-3 and …

2020年2月3日 · Ferroptosis is a new type of programmed cell death, which occurs with iron dependence. Activating or blocking the ferroptosis pathway to alleviate the progression of the …

2023年1月5日 · To understand the crosstalk between apoptosis and ferroptosis, various organelle-specific mechanisms must be analyzed and compared. The ability to switch …

2021年7月26日 · Ferroptosis as a novel form of cell death differs from other cell death such as apoptosis, necroptosis, pyroptosis and autophagy-dependent cell death. Ferroptosis is closely …

2022年1月17日 · We describe the cell morphological features and molecular mechanisms of pyroptosis, apoptosis, necroptosis, and ferroptosis, and summarize the current research …

2024年2月11日 · This study provides novel insights into how molecular crosstalk occurs around mitochondrial membranes to trigger ferroptosis and apoptosis, with significant implications for …

2024年1月24日 · One study suggests that ferroptosis is morphologically and biochemically distinct from autophagy, apoptosis, and necrosis [1]. It differs from the morphological characteristics of …

In this review, we first elucidate core mechanisms of ferroptosis and summarize its epigenetic modifications (e.g., histone modifications, DNA methylation, noncoding RNAs, and …

2024年1月4日 · Apoptosis, necroptosis, pyroptosis, and ferroptosis are four forms of regulated cell death in mammalian cells that are controlled by distinctive biochemical pathways and have …

Ferroptotic agents induce the unfolded protein response and subsequently ER stress-mediated activation of the PERK-eIF2α-ATF4-CHOP pathway. CHOP (C/EBP homologous protein) …