In organic chemistry, a carbodiimide (systematic IUPAC name: methanediimine [1]) is a functional group with the formula RN=C=NR. On Earth they are exclusively synthetic, but in interstellar …

Carbodiimide compounds provide the most popular and versatile method for labeling or crosslinking to carboxylic acids. The most readily available and commonly used carbodiimides …

2021年10月14日 · Carbodiimide is a group of reagents that crosslinks amines and carboxylates, that may be used as a fixative and in peptide conjugation.

Common carbodiimides used for coupling are 1-ethyl-3-(3-dimethyl-aminopropyl) carbodiimide hydrochloride (EDAC), 1-cyclohexyl-3-(2-morpholinyl-4-ethyl) carbodiimide methyl p-toluene …

The carbodiimide formation process not only produces the main product CDIs but also carbon dioxide as a significant byproduct; nevertheless, other side reactions produce different species.

The water-soluble carbodiimide, 1-ethyl-3-(3-(dimethylaminopropyl)-carbodiimide (EDC) is widely used in protein chemistry. We used EDC-induced gelatin cross-linking as a model for amide …

Carbodiimide-based synthesis of N-heterocycles: moving from two classical reactive sites to chemical bond breaking/forming reaction. Chemical Society Reviews 2020 , 49 (16) , 5810-5849.

2024年7月24日 · A generic carbodiimide. Carbodiimides are a type of dehydrating chemical most often used to activate carboxylic acids for subsequent coupling with primary amines , …

A carbodiimide is a functional group consisting of the formula N=C=N. Carbodiimides hydrolyze to form ureas, which makes them rarely found in nature.

2007年9月7日 · Carbodiimides play an important role as condensation agents in the synthesis of polypeptides, polynucleotides, polysaccharides and numerous other chemical transformations. …