Azole antifungal agents can be used to treat fungal infections of the body and skin, including athlete's foot, onychomycosis (fungal nail infections), ringworm, and vaginal candidiasis.

2024年12月3日 · Azole antifungals are used to treat thrush, yeast infection, candidiasis, tinea versicolor, athlete's foot, jock itch, ringworm, nail fungus, fungal infections, and seborrheic dermatitis. They work by slowing down and preventing the growth of fungus.

2024年8月3日 · Azole antifungals are generally well tolerated but are involved in numerous drug-drug interactions. Look carefully for interactions before initiating these (use a drug-interaction tool such as 燐 MedScape's drug interaction checker.)

Overview of the pharmacology, mechanism of action, and clinical uses of azole antifungals.

The azole antifungal agents in clinical use contain either two or three nitrogens in the azole ring and are thereby classified as imidazoles (e.g., ketoconazole and miconazole, clotrimazole) or triazoles (e.g., itraconazole and fluconazole), respectively.

Investigated for use/treatment in fungal infections, bacterial infection, skin infections/disorders, and onychomycosis. A topical antifungal used to treat pityriasis capitis and seborrheic dermatitis. A triazole antifungal used to treat various fungal infections including candidiasis.

Amphotericin B, an effective but relatively toxic medication, has long been the mainstay of antifungal therapy for invasive and serious mycoses. However, newer potent and less toxic triazoles and echinocandins are now often recommended as first-line drugs for many invasive fungal infections.

Factsheets about azole antifungals (posa, vori, itra, fluc, keto, eco, clotrim). Formulations, dosages, activity, PK, drug interactions, toxicity

2024年3月1日 · The primary mechanism of action involves the inhibition of ergosterol biosynthesis, leading to the disruption of fungal cell membrane integrity. Exploring these azole antifungal agents involves covering indications, contraindications, drug …

2024年10月17日 · Azole antifungals are key in treating fungal infections, important in both clinical and agricultural settings. They treat a range of pathogenic fungi affecting humans and animals. However, rising resistance highlights the need to understand azoles for effective strategies against fungal pathogens.