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    Is guanylin a peptide?
    Guanylin is a peptide hormone that is produced in various tissues of mammals, particularly in the gastrointestinal tract, and plays a role in regulating fluid secretion during digestion and kidney function. You might find these chapters and articles relevant to this topic. Leonard Ralph Forte, in Encyclopedia of Gastroenterology, 2004

    Guanylin - an overview | ScienceDirect Topics

    sciencedirect.com
    What is uroguanylin & guanylin?
    Jeffrey M. McKenna, in Annual Reports in Medicinal Chemistry, 2011 Uroguanylin and guanylin are peptide hormones which bind to the guanylate cyclase C (GC-C) receptor in the gut epithelium.

    Guanylin - an overview | ScienceDirect Topics

    sciencedirect.com
    Where is guanylin found?
    Leonard Ralph Forte, in Encyclopedia of Gastroenterology, 2004 Guanylin and uroguanylin, peptide hormones that are produced in all tissues of placental (i.e., eutherian) mammals, are found most abundantly within epithelial cells of the gastrointestinal tract.

    Guanylin - an overview | ScienceDirect Topics

    sciencedirect.com
    Are guanylin peptides vasoactive?
    The guanylin family consists of guanylin and uroguanylin, the latter being also synthesized in the kidney where it exerts potent natriuretic effect in mammals (Forte et al., 2000 ). Guanylin peptides do not seem to have vasoactive properties.

    Guanylin - an overview | ScienceDirect Topics

    sciencedirect.com
    Where is guanylin expressed in the GI tract?
    Guanylin and uroguanylin have been reported to exhibit differential expression along the GI tract, with Guca2b mainly expressed in the proximal small intestine and Guca2a mainly expressed in the distal small intestine and the colon 16, 36.

    Characterisation of proguanylin expressing cells in the intestine

    nature.com
    Does guanylin secrete peptides in goblet cells?
    This finding was observed in both mouse and human intestine and is consistent with the localisation of guanylin-expression in goblet and Paneth cells, which are specialised to secrete peptides and mucus in the luminal direction.

    Characterisation of proguanylin expressing cells in the intestine

    nature.com
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