Radiosensitivity is the relative susceptibility of cells, tissues, organs or organisms to the harmful effect of ionizing radiation. Cells are least sensitive when in the S phase, then the G 1 phase, then the G 2 phase, and most sensitive in the M phase of the cell cycle.

The radiosensitivity is the proneness to the adverse tissue events that are considered as non-cancer radiation-induced effects and attributable to cell death. Radiosensitivity is generally correlated with unrepaired DNA damage ;

Radiosensitivity is the response of the tumor to irradiation that can be measured by the extent of regression, rapidity of response, and response durability. Radiosensitivity depends on several factors.

Radiosensitivity is the proneness to radiation-induced adverse tissue events after high doses of IR, essentially after radiotherapy (the term radiosensitivity keeps here its historical meaning). In other words, radiosensitivity would be related to non-cancer effects attributable to cell death;

2022年12月7日 · In this Review, we summarize the effect of these pathways on tumour responses to radiotherapy and the current state of research on genomic classifiers designed to exploit these variations to...

2021年7月2日 · In parallel, the predisposition to radiation-induced adverse tissue reactions (radiosensitivity), notably observed after radiotherapy appears to be caused by different mechanisms than those linked to predisposition to radiation-induced cancer (radiosusceptibility).

Radiosensitivity is a multi-dimensional problem (Figure 1) that spans levels of tissue organization (DNA, cells, tissues), time (from seconds to decades), people (individuals, families and populations), patients (gender, age, health and disease), and physics (modalities, doses and radiation quality) and describes a spectrum of outcomes that are ...