Sodium butyrate is a compound with formula Na(C 3 H 7 COO). It is the sodium salt of butyric acid. It has various effects on cultured mammalian cells including inhibition of proliferation, induction of differentiation and induction or repression of gene expression. [1] As such, it can be used in lab to bring about any of these effects.

2022年7月11日 · A sodium butyrate supplement may help with irritable bowel syndrome (IBS), diverticulitis and Crohn’s disease.

Sodium butyrate is an organic sodium salt resulting from the replacement of the proton from the carboxy group of butyric acid by a sodium ion. It has a role as an EC 3.5.1.98 (histone deacetylase) inhibitor and a geroprotector.

2019年10月25日 · Butyric acid is a fatty acid that’s created when the good bacteria in your gut break down dietary fiber. It’s also found in animal fats and vegetable oils. However, the amount of butyric acid...

2022年1月5日 · Butyrate (also known as butyric acid or sold in supplement form as sodium butyrate) is one of a family of short-chain fatty acids, or SCFAs. The two other common SCFAs are acetate and propionate.

Short-term oral administration of sodium butyrate alleviates diet-induced obesity and insulin resistance through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle

Sodium butyrate is a short-chain fatty acid that inhibits histone deacetylase (HDAC) in the millimolar range. Decreases Ca 2+ release from intracellular stores. Induces apoptosis in several cell lines. Sodium butyrate induces the production of recombinant protein in Chinese hamster ovary (CHO) cells and other human cell lines.

2024年10月14日 · Sodium butyrate, being a salt form of butyric acid, dissociates into sodium ions and butyrate ions upon dissolution in aqueous solutions. This dissociation process is influenced by various factors, including pH, temperature, and …

Sodium butyrate is a well-characterized inhibitor of Class I and Class II HDACs (Table 18.1) used in many experiments studying eukaryotic histone modification. It is a water-soluble molecule with an unpleasant odor.

2024年5月31日 · Butyrate is available in dietary supplements (often in the form of sodium butyrate or calcium/magnesium butyrate), though there are potential risks and benefits associated with using these SCFAs to boost butyrate levels in the body.