Diosgenin is a phytochemical that has acquired prominence due to its usefulness in the treatment of lethal diseases such as nervous system disorders, diabetes, cancer, arthritis, asthma, cardiovascular disease, and others .

Wild yam is a plant that has been promoted as natural DHEA because it contains diosgenin, which can be used in the lab to create estrogen and DHEA. There are over 600 species of wild yams.

Diosgenin is a sapogenin that is spirostan which is substituted by a hydroxy group at the 3beta position, contains a double bond at the 5-6 position, and has R- configuration at position 25. A natural product found in Dioscorea (wild yam) species, it is used as the starting point for the commercial synthesis of a number of steroids, including ...

Diosgenin is a steroidal sapogenin known for years for its interesting bioactivity, and accordingly a large amount of studies has been performed to explore its potential interest in a large variety of medical conditions.

2023年10月1日 · Diosgenin is an isospirostane derivative, a steroidal sapogenin, and the product of acids or enzymes hydrolysis process of dioscin and protodioscin (Shahrajabian et al., 2021). It is considered an important precursor of steroidal drugs.

2022年5月29日 · This review aims to provide an overview of the in vitro, in vivo, and clinical studies reporting the diosgenin's pharmacological effects and to discuss the safety issues. Preclinical studies have shown promising effects on cancer, neuroprotection, atherosclerosis, asthma, bone health, and other pathologies.

Diosgenin, a phytosteroid saponin, is found at high levels in several plant species, including Costus speciosus, Smilax menispermoidea, Trigonella foenum, species of Paris, Aletris, Trigonella, and Trillium, and many species of Dioscorea (Patel et al., 2013; Chen et al., 2011).

2024年5月3日 · Diosgenin, a unique steroidal saponin, offers a variety of pharmacological benefits due to its distinctive chemical structure. To fully harness its therapeutic potential, it is crucial to thoroughly understand its chemical and physical properties, including its stereochemistry, stability, and spectroscopic characteristics.

2020年3月6日 · 3. Sources of Diosgenin. Primary sources of diosgenin (DG) include the Dioscorea species, Heterosmilax species, and Trigonella foenum-graecum, although DG and related steroidal sapogenins can be commercially obtained from tubers of various Dioscorea species [].DG is present in high levels in tubers of various wild yams (D. villosa Linn).A total of …

2023年11月27日 · Diosgenin is a phytosteroid sapogenin isolated from a variety of botanicals. The main source is the genus Dioscorea, tropical wild yam species of the genus Dioscorea that are native to Asia and are now cultivated in other continents.