2023年11月22日 · L-Histidine - structure, chemical names, physical and chemical properties, function

Histidine ball and stick model spinning. Histidine (symbol His or H) [2] is an essential amino acid that is used in the biosynthesis of proteins.It contains an α-amino group (which is in the protonated –NH 3 + form under biological conditions), a carboxylic acid group (which is in the deprotonated –COO − form under biological conditions), and an imidazole side chain (which is …

Learn more about HISTIDINE uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain HISTIDINE.

2024年9月9日 · Because L-histidine is an essential amino acid, the body doesn’t make it naturally. Therefore, it must be consumed in food. Some people also take supplements to increase their levels of L-histidine, believing that the boost can prevent heart disease or improve several conditions, such as rheumatoid arthritis.

2023年7月30日 · Histidine is a nutritionally essential amino acid precursor for several hormones (eg, thyrotropin-releasing hormone) and critical metabolites affecting renal function, neurotransmission, gastric secretion, and the immune system. Histidine's unique acid/base properties make it a versatile catalytic residue in many enzymes and for those proteins and …

L-histidine (HIS) is an essential amino acid with unique roles in proton buffering, metal ion chelation, scavenging of reactive oxygen and nitrogen species, erythropoiesis, and the histaminergic system. Several HIS-rich proteins (e.g., ...

Catabolic pathways of histidine [].Urocanic acid has a protective role against harmful effects of ultraviolet rays on the skin. It is metabolized in the liver to 4, 5-dihydri-4-oxo-5-imidazolepropanoic acid by urocanate hydratase, and is then converted to formimino-glutamate (FIGLU) and N 5-formimino-tetrahydro-folate.In epiderma, urocanate hydratase is not present, and urocanic …

Since the actions of supplemental L-histidine are unclear, any postulated mechanism is entirely speculative. However, some facts are known about L-histidine and some of its metabolites, such as histamine and trans-urocanic acid, which suggest that supplemental L-histidine may one day be shown to have immunomodulatory and/or antioxidant activities.. Low free histidine has …

Histidine, an amino acid obtainable by hydrolysis of many proteins. A particularly rich source, hemoglobin (the oxygen-carrying pigment of red blood cells) yields about 8.5 percent by weight of histidine. First isolated in 1896 from various proteins, histidine is one of several so-called essential

Fates of histidine in the human body. CNS, central nervous system. Histidine Catabolism. Figure 2 shows the metabolic pathway for histidine metabolism. Histidase (histidine ammonia lyase) is the first and principal regulatory enzyme in the pathway, producing ammonia and trans-urocanate.It is a cytosolic enzyme, principally found in skin and liver, with a Km for histidine in …