Gout attacks are caused by inflammation in joints that arises from reaction to crystals of urate. Gout, which is often associated with binge drinking or eating poorly, may be more genetically ...

A new study finds that obesity significantly reduces the effectiveness of urate-lowering therapy in male gout patients, with ...

Arthrosi Therapeutics, Inc., a late-stage biotechnology company developing a potentially best-in-class, highly potent and selective next generation URAT1 inhibitor to reduce serum urate (sUA) levels, ...

Monosodium urate crystals dissolve and are eliminated from joints and soft tissues as serum uric acid levels drop below its saturating point (400 μmol/l). Time to crystal clearance relates to ...

Among patients with gout in the US, Black individuals and those living in the South were associated with reduced adherence to allopurinol.