One of the key areas of research has been the identification of genetic polymorphisms that affect thiopurine metabolism. For instance, variations in the TPMT gene can lead to different levels of ...

This study aimed to critically appraise the current level of economic evidence available for thiopurine S-methyltransferase (TPMT) testing of thiopurine drugs, such as azathioprine. Six economic ...

Objectives Patients with SLE take multiple medications. Within a large prospective longitudinal SLE cohort, we characterised ...

Researchers have uncovered differences in how patients with South Asian and white ethnicity present with inflammatory bowel ...

Dermatitis. 2006;17(4):165-181. There are very few randomized controlled trials that have evaluated treatments of hand dermatitis in general. [61] A review of published trials that involved the ...

Several new treatment modalities with different mechanisms of action have been studied in patients with Behçet’s syndrome (BS). The aim of the current effort was to update the recommendations in the ...

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1 Department of Gastroenterology, The People’s Hospital of Yubei District of Chongqing City, Chongqing, China 2 Department of Ultrasound, The People’s Hospital of Yubei District of Chongqing City, ...

et al. Optimizing thiopurine therapy in autoimmune hepatitis: A multicenter study on monitoring metabolite profiles and co-therapy with allopurinol[J]. Hepatology 2024; 80(5): 1026-1040. [4] Rivei ...

Objectives B-cell depletion time after rituximab (RTX) treatment is prolonged in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) compared with other autoimmune diseases. We ...