Frizzled (Fz)/planar cell polarity (PCP) signalling is a conserved mechanism regulating the polarity of cells along the axes of a tissue. Fz/PCP regulates a diverse array of processes including ...

The primary cilium is a narrow organelle located at the surface of the cell in contact with the extracellular environment. Once underappreciated, now is thought to efficiently sense external ...

The vertical movements of the basilar and tectorial membranes generate shearing forces that deflect the hair cell stereociliary bundles. Bending of the stereocilia opens mechanosensitive channels near ...

Prestin is an integral membrane motor protein located in outer hair cells of the mammalian cochlea. It is responsible for electromotility and required for cochlear amplification. Although prestin ...

Background Countries with culturally accepted consanguinity provide a unique resource for the study of rare recessively inherited genetic diseases. Although hereditary hearing loss (HHL) is not ...