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PNAS发现胰腺癌高侵袭性的关键
胰腺癌是最具侵袭性的癌症之一,也是存活率最低的癌症之一,5年后只有10%。造成其侵袭性的因素之一是其肿瘤微环境,即间质,它构成了肿瘤肿块的大部分,由蛋白质网络和不同的非肿瘤细胞组成。其中,成纤维细胞起着关键作用,帮助肿瘤细胞生长并增加其对药物的抵抗力。现在,由del Mar医院研究所IIBB-CSIC-IDIBAPS、Mayo诊所、Biología ...
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