Within 7SK snRNP, Tat may replace HEXIM1 from the 7SK 5′-hairpin structure and P-TEFb via its ARM and activation domain, respectively, and thus remove it from its preferred position.

Plants are very important living things. They have lots of jobs, such as providing animals with food and releasing oxygen into the air. To survive and carry out these jobs, they all need three ...

Exposure to exogenous particles found as airborne contaminants or endogenous particles that form by crystallization of certain nutrients can activate inflammatory pathways and potentially accelerate ...