Using a collision technique, the ulnar nerve was made refractory for a shorter distance normally covered in 0.5 ms or a longer distance covered in 1.5 ms. Studying the shorter refractory segment with ...

Apathy is increasingly recognised as a common behavioural syndrome in psychiatric disorders, but it is conceptually ill defined. The aim of this study was to examine the concept of apathy as it is ...

Dr O Hardiman, Department of Neurology, Beaumont Hospital, and Trinity College Institute for Neuroscience, Trinity College Dublin, Dublin 9, Ireland; ohard{at}iol.ie Background: We conducted a ...

Loss of nigrostriatal dopaminergic projection neurons is a key pathology in Parkinson’s disease, leading to abnormal function of basal ganglia motor circuits and the accompanying characteristic motor ...

Correspondence to Dr Michael Benatar, Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA; MBenatar{at}med.miami.edu Notwithstanding the challenges, it is ...

3 Working Group ‘Deep Brain Stimulation in Psychiatry: Guidance for Responsible Research and Application’. This Working Group is organised by the Europäische ...

Parkinson’s disease (PD) is an incurable and progressive neurological disorder leading to deleterious motor and non-motor consequences. Presently, no pharmacological agents can prevent PD evolution or ...

Traumatic brain injury (TBI) leads to increased rates of dementia, including Alzheimer’s disease. The mechanisms by which trauma can trigger neurodegeneration are increasingly understood. For example, ...

1 Danish Headache Centre, Department of Neurology, Glostrup Hospital, University of Copenhagen, Denmark 2 Department of Neurosurgery, Rigshospitalet, University of Copenhagen, Denmark Correspondence ...

The immune system has long been recognised important in pain regulation through inflammatory cytokine modulation of peripheral nociceptive fibres. Recently, cytokine interactions in brain and spinal ...

As a chronic progressive disease, Parkinson's disease (PD) has a presymptomatic interval; that is, a period during which the pathological process has begun, but motor signs required for the clinical ...

Correspondence to Professor Yong-Ping Chen, Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China; Yongping.chen{at}wchscu.cn Background Alzheimer’s disease (AD) is ...