Synaptic efficacy is a basic concept in neuroscience for which we have an intuitive definition — the capacity of a presynaptic input to influence postsynaptic output. Similarly, we have an ...

They should also be capable of trans-synaptic signaling and act to redistribute pre- and postsynaptic proteins. A prime example of such an inducer is agrin. A neuron-specific splice variant of ...

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent continuous stimulation of postsynaptic neurons. There are two types of removal: Re-uptake – the ...

This results in enough neurotransmitter being diffused across the synaptic cleft to trigger the impulse in the postsynaptic neuron. This process is called summation.