Nephrotoxicity, the major complication of long-term therapy with amphotericin B, is attributed to drug-induced renal vasoconstriction plus a direct toxic action on renal tubules. Hypokalemia and ...

In addition, most current data on SH were based on retrospective studies. To address this knowledge gap, this prospective study aimed to address the efficacy and safety of the SH protocol administered ...

Proteinuria is the presence of too much protein in the urine. It is typically a sign of kidney disease, often in people diagnosed with diabetes, but also can occur with pregnancy, lupus, and other ...

The resubmitted NDA for sotagliflozin for adults with T1D and CKD included post hoc analyses from the TANDEM clinical development program and post hoc analysis from the SCORED trial.

Researchers have identified six new biomarkers that could detect kidney injury faster and with more sensitivity, advancing safer drug development and improving health outcomes for patients.

In sibling comparisons, there was no association seen between NSAID use and fetal nephrotoxicity. In singleton-born children, increased risks were seen for exposure during the second and third ...