LN的流行病学特征复杂多样,受种族、地域、社会经济等多种因素影响;其发病机制涉及遗传、环境(包括紫外线、空气污染、病毒感染、肠道菌群与食物因素)、免疫等多个方面,是多种因素相互作用的结果。深入研究这些方面,有助于开发更精准的诊断方法和更有效的治疗策略 ...
In a new study, researchers investigated microRNA-203 as a potential biomarker for lupus nephritis (LN) and found that ...
1 The purpose of ALMS was to demonstrate the superiority of mycophenolate mofetil (MMF) over intravenous cyclophosphamide for the induction of remission in patients with lupus nephritis.
March is here, and as we observe Kidney Month, it’s crucial to raise awareness about how lupus can severely impact the ...
1 More than 1.5 million people develop one of the most dangerous manifestations of SLE: lupus nephritis (LN), characterized by immune system induced inflammation of the kidneys. Within 10 years ...
Adding the anti-CD20 monoclonal antibody obinutuzumab (Gazyva) to standard therapy for lupus nephritis is more efficacious ...
For patients with active lupus nephritis, obinutuzumab, a humanized type II anti-CD20 monoclonal antibody plus standard ...
Adding obinutuzumab to standard therapy for active lupus nephritis led to significantly higher rates of complete renal ...
Nat Clin Pract Nephrol. 2007;3(6):296-297. How did this transfer of 'ownership' of lupus nephritis to rheumatologists happen? There are two possible reasons. Either rheumatologists hijacked lupus ...
The following is a summary of “Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis,” published in the February 2025 ...