This important work identifies a non-autophagic role for ATG5 in lysosomal repair and the trafficking of the glucose transporter GLUT1 to the cell surface, mediated through the retromer complex. The ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. This study identifies a pathway for oxidation ...

Notably, LCR4-induced complexes correlated with the formation of microscopically visible multimeric condensates. Adjacent to LCR4, we mapped a conserved domain (CD2) promoting condensates only.

Figure 1: Two-hybrid interactions between the PcG protein EED and HDAC2. Figure 3: Co-immunoprecipitation of EED, EZH2 and histone deacetylase activity from human 293 cells. Figure 4: Incubation ...