结直肠癌(CRC)是一种常见且死亡率较高的恶性肿瘤,严重威胁着人类健康。在 CRC 的复杂分子机制中,凋亡相关基因的异常表达往往扮演着重要角色。BCL2 - 样 12(BCL2L12)基因作为凋亡调控家族的一员,虽已被发现多年,但围绕其环状转录本的研究却相对匮乏,这就如同在探索 CRC 发病机制的拼图中,缺失了重要的几块。为了填补这一空白,深入了解 CRC ...
Chen, F. (2025) Advances in the Application of Deep Learning in Prognostic Models for Non-Small Cell Lung Cancer. Health, 17, ...
结直肠癌(CRC)危害大,研究人员探究线粒体编码环状 RNA SCAR/mc-COX 2 ,发现其或为抑癌因子和诊断标志物。 肿瘤微环境(Tumor Microenvironment,TME)在 CRC 的发展中起着关键作用,其中线粒体功能障碍引发的肿瘤代谢重编程,即 Warburg 效应,尤为突出。肿瘤细胞通过这种效应改变能量产生方式,同时生成活性氧(Reactive Oxygen ...
Former talk show host Wendy Williams took steady aim at her court-appointed guardianship in an interview with "The View" ...
LncRNAs and circRNAs are key regulators of gene expression, influencing disease mechanisms and offering potential as ...
They showed that shutting down a damaged copy of a gene called a microRNA (miRNA) enabled ... Novel Genome Editing Approach Restores Hearing in Adult Preclinical Models With Genetic Deafness July ...
A Florida teenager was kidnapped and possibly dismembered after meeting up with a man she met through a social media ...
Researchers from SRM Institute of Science and Technology, led by Dr. KN Aruljothi, have published a study in ExRNA ...
An international study led by the University of Granada (UGR) has revealed that melatonin, known for its ability to regulate the sleep/wake cycle, can restore the composition of muscle fibers and ...
随着生物信息学和人工智能的不断进步,越来越多的创新工具进入了科研人员的视野,推动了科学研究的快速发展。在这些工具中,AlphaFold 3无疑是近年来最为引人注目的一个。作为DeepMind团队推出的最新版本,AlphaFold 3不仅在蛋白质结构预测方面展现了突破性的进展,还通过开源的形式让全球的科研人员能够利用这个强大的工具。 随着大数据技术和人工智能(AI)的飞速发展,生物信息学领域也迎来了 ...
A small team of materials scientists and chemical engineers at Qingdao University, in China, has developed a self-powered, three-component biosensor that can kill bacteria in water samples. The ...