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生物通
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“第二代” DNA 甲基化预测指标与代谢综合征及 2 型糖尿病的关联 ...
为探究哪些基于 DNA 甲基化(DNAm)的预测指标与代谢综合征(MetS)和 2 型糖尿病(T2D)密切相关,研究人员对 KORA 研究中参与者进行相关分析。结果发现 GrimAA、PhenoAA 差异和死亡率风险评分(MRS)与 MetS 和 T2D 显著相关,这为疾病风险分层和预后提供了潜在生物标志物。
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