Epigenetic alterations have emerged as critical factors in the pathogenesis of brain cancer, particularly gliomas. This article explores the impact of organochlorine pesticides (OCPs) on the ...

With the strong associations established in epidemiologic studies and a dearth of evidence on the actual mechanisms by which ...

DURECT Corporation (Nasdaq: DRRX) today announced that James E. Brown, President and Chief Executive Officer, will present at ...

Mutations of the isocitrate dehydrogenase (IDH) 1 and 2 genes occur in ~80% of lower-grade (WHO grade II and grade III) gliomas. Mutant IDH produces (R)-2-hydroxyglutarate, which induces DNA ...

TBC1D30 also has been shown to be highly methylated in colorectal cancer. NELL1 has been shown to be a diagnostic marker of both Barrett's esophagus and colorectal cancer, and hypermethylation of ...

TBC1D30 also has been shown to be highly methylated in colorectal cancer. NELL1 has been shown to be a diagnostic marker of both Barrett’s esophagus and colorectal cancer, and hypermethylation of ...