近日，西湖大学吴连锋团队在 Cell Reports 杂志发表了一篇题为“Non-canonical hepatic androgen receptor mediates glucagon sensitivity in female mice through the PGC1α/ERRα/mitochondria axis”的最新研究成果。该研究揭示了肝脏雄激素受体在小鼠胰高血糖素调节葡萄糖和脂质 ...

1). The company’s lead hepatic program, OLX702A, is being developed for the treatment of NASH, a common liver disease characterized by the accumulation of liver fat, inflammation, and ...

A research team has identified the transcription factor Lhx2 (LIM homeobox protein 2) as a key regulator in hepatic stellate cells. Lhx2 was found to simultaneously promote liver regeneration and ...

Symptoms that are sometimes diagnosed as part of dementia might actually be related to a treatable liver condition, according ...

Hepatic fibrosis is a reversible wound healing response characterized by accumulation of extracellular matrix (ECM), or "scar," that follows chronic but not self-limited liver disease. The ECM ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Patients with cirrhosis and minimal hepatic encephalopathy often experience sleep difficulties, but treatment with benzodiazepines is frequently ineffective and can have serious side effects.

Ex-Takeda VP Tauhid Ali, Ph.D., with broad leadership and drug development experience becomes Board DirectorSeasoned regulatory strategist Darren ...

Acute and chronic treatment for hepatic encephalopathy acquired from Mallinckrodt Pharmaceuticals in September 2024Extended pre-clinical, ...

Oral contraceptive pills (OCPs) are commonly used for contraception, but their long-term effects on oxidative stress, lipid profiles, and liver function remain unclear. This study aimed to evaluate ...