State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China University of Chinese Academy of Sciences, Beijing 100049, China ...

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Atherosclerosis is a chronic lipid-driven and maladaptive inflammatory disease of arterial intima. It is characterized by the dysfunction of lipid homeostasis and signaling pathways that control the ...

为了解决上述问题，中国科学院上海药物所李铁海课题组于2025年2月11日在Journal of the American Chemical Society上发表了题为 “Host-Guest Chemistry-Mediated Biomimetic Chemoenzymatic Synthesis of Complex Glycosphingolipids ” 的文章 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Algorithms that constrain metabolic network ...

AL01211 is an orally available small-molecule inhibitor of glucosylceramide synthase, an enzyme that facilitates the first step in the formation of glycosphingolipids, a type of fatty molecule that ...