For years, scientists studying brain aging have focused on proteins and DNA. But what if a crucial piece of the puzzlehas ...

内皮糖萼失调会导致血脑屏障功能障碍，这与老年性痴呆的发生和发展密切相关。当内皮糖萼受损时， 血脑屏障的通透性 增加，血液中的有害物质更容易进入大脑，从而引发一系列 神经炎症 反应，导致大脑功能逐渐衰退。

The following is a summary of “Net albumin leakage in patients in the ICU with suspected sepsis. A prospective analysis using ...

In a study with aging mice, Shi discovered significant changes in the sugary coating (glycocalyx) on cells that form the blood-brain barrier. This barrier protects the brain by filtering harmful ...

但希望之光已然显现：研究者通过腺相关病毒（AAV）基因治疗，将衰老小鼠脑血管的糖萼厚度恢复83%，不仅逆转血管渗漏，更让20月龄老年鼠在迷宫测试中展现超越年轻组的空间记忆能力。这项颠覆性发现不仅重新定义了血脑屏障的防御机制，更为对抗阿尔茨海默病开辟了全新治疗维度：修复纳米级的糖萼结构，或将成为阻止大脑"塌方式衰老"的关键突破口。

In a study in aging mice, Shi has uncovered striking age-related changes in the sugary coating—called the glycocalyx—on cells that form the blood-brain barrier, a structure that protects the brain by ...

Shi was able to demonstrate that in this sugary layer called the glycocalyx, branched glycoproteins called mucins are an important component. Shi also observed that the number of mucins compared ...

A barrier against bacteria Epithelial cells that line the small intestine are protected by a carbohydrate-rich layer called the glycocalyx, which prevents bacteria from coming in direct contact ...

Epithelial cells that line the small intestine are protected by a carbohydrate-rich layer called the glycocalyx, which prevents bacteria from coming in direct contact with the cells. A key ...

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