Several lines of evidence have demonstrated that deregulated activation of NF-κB plays a pivotal role in the initiation and progression of a variety of cancers including multiple myeloma (MM).

Renowned for centuries, Ginkgo biloba is a well-known herbal supplement famed for its potential to bolster cognitive function, memory, and overall brain health. Sourced from the leaves of the ...

此外，SUMO 化修饰抑制剂银杏酸（Ginkgolic Acid，简称 GA）可以显著减轻缺氧诱导的血管内皮损伤和炎症反应。这一研究揭示了 FADD 的 SUMO 化修饰在缺氧介导的内皮细胞坏死性凋亡中的新机制，为缺氧相关心血管疾病的治疗提供了潜在的靶点，就像在黑暗中找到了 ...

Gastric cancer (GC) is a prevalent malignant tumor that originates from the epithelial cells of the gastric mucosa, predominantly in the form of adenocarcinoma. Extensive research has confirmed the ...

Proteins in cells carry out diverse tasks. One way in which this diversity is achieved by proteins is through the attachment of molecular tags. SUMO is one such tag that can reversibly attach to ...